Technology

Chemistry and microbiology scientists at Ryerson University in Toronto Canada became intrigued with the interface between surfaces and biofilm forming microorganisms. Realizing that the problems of drug resistant microbes were aggravated by chemistries that leached from surfaces at sub-lethal levels, they searched for a better way of controlling the microbes and biofilms using surface modifying technologies. Inspired by the organo functional silane antimicrobial developed at Dow Corning, the researchers sought and found better bonding technologies that increased the durability and antimicrobial performance on medical devices and medical-related products made of metals, plastics and fabrics. The researcher’s discovery is the basis for patented technologies that anchor Nano Safe Coatings to various substrates.

Nano Safe Coatings offers three patent and patent-pending products to meet the specific needs of the medical device and products industry. Which technology is used largely depends on the substrate the treatment is applied. Nano Safe Coatings is anchored to metal using organophosphate and to plastics using benzophenone. Efficacy is achieved by using heat for metals and UV exposure for plastics.

In addition to the two technologies, scientists at Ryerson University have added a sulfonamide to the tip of the nano-spikes, which adds another layer of defense against microbes and biofilm build up. The sulfonamide can be added to the treatment process for both metals and plastics.
Whether the substrate is metal or plastic will determine how the treatment is applied. Typically it is done by misting, spraying or dipping the device or product. We will work with you to determine which application method is best for your device or product. Once an agreement and commercialization plan is in place, we can determine whether the treatment is applied in your facility or by an approved outsourcing-contractor.

When treated, the C-18 carbon molecule provides a protective, consistent and sustainable barrier that is constantly killing bacteria, fungus, mold-spores and viruses on the substrate where the coating is applied. Nano Safe Coatings technology provides an ionic bed that kills mechanically by disrupting the cell membrane. As a result, the technology does not promote superbugs, which are becoming increasingly more resilient to traditional antimicrobial and antibiotic therapies. In addition, the coating eliminates biofilm by killing the microbes on contact, not by leaching into the cell walls like most antimicrobials on the market today.

Unlike its competitors, Nano Safe Coatings is water-based; it works on both porous and non-porous surfaces, and does not use poisons or metals (e.g. silver, copper or zinc). Many antimicrobial products currently on the market are under scrutiny for potential health concerns and environmental problems because of their leaching and migrating properties. Some of them including Triclosan have already been banned in several countries and throughout the European Union.

Exhaustive testing has proven a six-log or greater reduction in only three hours on surfaces treated with Nano Safe Coatings. Regardless of the substrate – metals, plastics or fabrics – such reductions are not attainable with most other antimicrobial technologies even after being exposed to test microbes for 24-hours. Nano Safe Coatings patented and patent-pending technologies provide permanent chemical bonds, which are customized for the medical device's composition, method of manufacture, and its predicted end-use and abuse. Nano Safe Coatings durability on substrates is also a distinguishing advantage over other antimicrobial/anti-biofilm technologies currently on the market. The anchor ensures a self-sterilizing surface that protects patients and caregivers from the constant threat of Healthcare-Acquired Infections (HAIs). In addition, our technology can withstand the repeated rigors of most sterilization and sanitation methods.

Nano Safe Coatings is the perfect antimicrobial protection for a variety of medical devices, wound-care products, sutures, hospital environments and a wide array of medical-related products.